At an urban Animal Shelter, a Maltese mix named Coco has a surprise litter, led by bold, only-boy Ralphie. While in the country, a restless Ragdoll kitten named Jolene might be more than her laid-back mom can handle.

A pair of Shetland Sheepdogs are concerned that their only pup is getting distracted by the farm's resident Pomeranian Gino. Plus, in a litter full of tailless Manx, one kitten named Charlie is born with a tail and needs to figure out he fits in.

In a home full of crafting supplies, an Abyssinian kitten gets into absolutely everything. Meanwhile, a hairless Elf kitten named Pixie finds herself left out by her five rambunctious brothers and searches for a friend in furrier places.

In a small town, a dog about town named Izzy brings a rare litter of Portuguese Podengo Pequeno pups into the world, led by go-getter Gisele. Meanwhile, an octuplet of Cockapoos train to be therapy dogs.

In a cozy home of Himalayans, a shy kitten named Hugo follows in his father's footsteps. While a rags to riches rescue mix brings her brood of puppies to their new dream home and only girl, Honey, makes an unlikely friend.

A pair of rescue kittens are welcomed into their foster home by a cat-loving rescue dog named Sweet Potato. While a Rhodesian Ridgeback pup named Rosie discovers, with the help of a lively older cousin, that swimming can be a whole lot of fun.

Twin Dachshund pups, Lulu and Betty, discover their different personalities with a little bit of guidance from their free spirit father. While a show pup in training, Chinese Crested Dotty, forms an unlikely friendship with rescue Pitbull Bryan.

In the lush suburbs, Chip, a Golden Retriever pup, tries to get in the middle of the action while a Great Dane born to an agility star mom finds her long legs aren't so conducive to being agile.

An aggressive and unpredictable cat aptly named Bear takes his toll on owner Hannah's love life. Will Hannah chose to keep her boyfriend or her cat? Recently engaged Matt loves fiancée Amanda, but hates her cats and has reached his breaking point.

Sean cozies up to pet scorpions, snakes, tarantulas and fiance Lindsey at home, but can't deal with Avery the rambunctious Sphynx cat. From the moment Leslie moved into her boyfriend David's home, Fifi the cat has made it clear she's not welcome.

Brian and Carre are overwhelmed and at a loss when they realize they're fostering a wild feral cat. Garret and Jenny have their hands full with Duf, a cat that goes from pleasant to vicious with zero warning.

Dr. Jeff Young & his crack team treat and save the lives of countless pets at one of the busiest clinics in America. In this episode, Jeff is faced with saving a dog that goes into cardiac arrest shortly after arriving at his clinic.

A 3 month-old micro pig with an injured leg requires surgery, but anesthesia could be deadly. A French Bulldog's routine dental exam becomes a complex operation. The team heads into the Rockies to help a couple who rescue sled dogs.

A dog is brought into the clinic with a suspected broken leg, but Dr. Jeff quickly diagnoses a far more serious condition requiring urgent surgery. Vet tech Tasha is forced to overcome her childhood fear of birds.

A golden retriever is rushed into surgery after swallowing a pacifier. When a stray dog is hit by a car in Oklahoma, Dr. Jeff & his team step up to save him, but they'll need to find the dog a home once he has recovered from surgery.

When a homeless man’s puppy breaks its paw, Dr. Jeff & his team put the animal’s welfare ahead of everything else. And when a dog in pain is brought in, x-rays reveal one of the worst cases of bladder stones the staff has ever seen.